nirmatrelvir will raise the stage or effect of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.rufinamide will lessen the level or impact of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.The effects of estazolam on milk output are unidentified. As a result of estazolam’